The hottest drug packaging problem to be solved 1

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It is understood that although China's pharmaceutical packaging industry has made progress, it is still relatively backward and chaotic, affecting the quality of drugs, which needs to be improved at present

drug packaging in China has experienced three stages. In the 1950s and 1960s, brown glass bottles, straw cartons, straight neck ampoules, etc. formed the packaging characteristics of that era. The drug packaging is bulky, but it is based on the principle of practicality. Type: single height, dark brown glass bottle (with cork and iron cover) for tablets, and large package (0.5g × 1000 tablets), less sugar coated tablets. Bottle stickers are designed with complex colors. The printing is mainly typesetting. Ink manuscripts are generally hand drawn, and small instructions are written with a duck beak pen, which is neat. Glass bottles are usually packed in straw board cartons and manual paste lined spacers. Corrugated paper partitions (teeth) are used for direct packing of more than 200 grams, which is heavy and inconvenient for transportation. The package of the water needle is single, mainly 1 ml, 2 ml and 5 ml, and the glucose for drip is filled with 20 ml straight neck ampoules, and the outer box is a folding carton. Cartons are pasted with boxes. The printing of box stickers is rough, and there are great differences between boxes and box stickers. The powder packaging is simple. The powder is directly packed in thin paper folded bags, and the outer and small writing paper bags are monotonous in color

the second stage is from 1970s to early 1980s. This stage is in a state of adjustment and hesitation. At this time, it was greatly affected by the "Cultural Revolution", especially from the late 1960s to the late 1970s, there was no registered trademark on the drug packaging, and it was slowly on track after a long period of pain

Since the 1980s, like other industries, the pharmaceutical packaging industry has developed healthily after years of running in. In the early 1980s, the registered trademark was restored and the drug packaging was improved. In terms of packaging form, in addition to tablets, powders, pills, creams, water, needles, powders, suppositories, oral liquids, aerosols, capsules, patches, chewing agents and other dosage forms have been developed. In terms of materials, aluminum plastic, paper plastic, laser anti-counterfeiting and other composite materials are gradually popularized. The annual output value of China's pharmaceutical packaging industry has reached more than 12 billion yuan, with more than 1100 manufacturers

the development and introduction of various new packaging machinery, together with the application of new packaging materials, have made China's pharmaceutical packaging industry take on a new look. The wide application of composite materials such as aluminum plastic, paper plastic, electrochemical aluminum, vacuum aluminum plating film and laser anti-counterfeiting has effectively improved the grade of drugs, also improved the level of packaging and packaging decoration, and gradually narrowed the gap with foreign counterparts. Aluminum plastic cover packaging of tablets is widely used, accounting for a considerable proportion in the market. The water needle eliminated the straight neck ampoule and replaced it with the curved neck easy to break ampoule. The quality of yellow bottle has been greatly improved. Composite bags are widely used in powders, tablets and granules. The printing on the capsule has been gradually introduced to the market

In the late 1990s, the popularity of computers also brought drug packaging design into a new era

at present, the current situation of pharmaceutical finished product packaging in China shows the following characteristics:

first, some pharmaceutical packaging pays attention to practical principles, which meets the requirements of pharmaceutical administration. Most of these drugs are Western medicines, which are products of joint ventures. These packaging and decoration designs are reasonable and exquisite, and the materials of cartons are exquisite. 1. The protection and maintenance of the material change experimental machine is strong, crisp, and feels good, which is representative to a certain extent

second, some drugs are poorly packaged, and the gains are not worth the losses. Among them, the proportion of Chinese patent medicine is significant. Some use straw paper and box paper as lining, which affects the running grid, and the impact resistance is extremely poor. If the sales place is wet and humid, the strength of the carton will weaken after moisture absorption, and it is easy to be damaged

III. The packaging of some drugs is soft. Most of them are packaged in tablets, especially sugar coated tablets. Due to their heavy weight and soft packaging, there are many opportunities for friction between tablets, and the phenomenon of peeling and cracking is serious

v. bottled rubber sealing materials that play a leading role in medical packaging training are natural rubber and butyl rubber. However, because the performance of natural rubber can not meet the requirements of drugs, it is vulnerable to pollution and is gradually eliminated in the world, while China has been using bottle stoppers made of natural rubber. Insiders believe that the disorderly competition in recent years has caused huge "hidden dangers" to the development of the pharmaceutical packaging industry. China's pharmaceutical packaging industry is far behind the international level in terms of packaging design and material selection

Zhang Heqing, President of China Pharmaceutical Packaging Association, believes that the awareness of pharmaceutical packaging should not become a "blind spot" in the pharmaceutical industry. In the future, we must strengthen the research and application of new packaging materials and vigorously develop advanced materials such as butyl rubber. The relevant administrative departments should further revise the measures for the administration of drug packaging issued 10 years ago to meet the requirements of the development of the times, establish new standards and rules in the pharmaceutical packaging industry, and gradually improve the safety and health quality standards and testing and evaluation methods of drug packaging products. Paul Gallen of NCC and Christian wolfsberger of Engel should not bring backward pharmaceutical packaging products into the 21st century. (Xu Guoying's good measurement and control software should reflect the advantages of modularization and humanization)

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